Diagnosis and Management of Inherited Palmoplantar Keratodermas

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Palmoplantar keratodermas: clinical and genetic aspects.

Palmoplantar keratodermas comprise a diverse group of acquired and hereditary disorders marked by excessive thickening of the epidermis of palms and soles. Early onset and positive family history suggest a genetic cause. While hereditary forms of palmoplantar keratoderma (PPK) may represent the sole or dominant clinical feature, they may also be associated with other ectodermal defects or extra...

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Diagnosis and Management of Inherited Platelet Disorders.

In clinical daily practice the definition of a bleeding tendency is rather subjective. Clinical manifestations usually include hematoma, epistaxis, menorrhagia, and severe bleeding episodes after surgery or injuries. The most common causes are disorders of primary hemostasis that occur sometimes due to platelet function disorders. Inherited thrombocytopathies are much less frequent in compariso...

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Punctate Palmoplantar Keratodermas: Case Reports and A Review of the Literature and Terminology

Keratodermas encompass a wide spectrum of disorders of keratinization that may be acquired or hereditary. We present two cases of focal acral hyperkeratosis (FAH), a subtype of punctate palmoplantar keratoderma. We review the literature and attempt to clarify the confusing classification of the heritable punctate palmoplantar keratodermas.

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Unique autosomal recessive variant of palmoplantar keratoderma associated with hearing loss not caused by known mutations*

Inherited Palmoplantar Keratodermas are rare disorders of genodermatosis that are conventionally regarded as autosomal dominant in inheritance with extensive clinical and genetic heterogeneity. This is the first report of a unique autosomal recessive Inherited Palmoplantar keratoderma -sensorineural hearing loss syndrome which has not been reported before in 3 siblings of a large consanguineous...

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ژورنال

عنوان ژورنال: Acta Dermato Venereologica

سال: 2020

ISSN: 1651-2057

DOI: 10.2340/00015555-3430